6 Results for "

CNO

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "CNO" in MCE Product Catalog:

Triflusal
Triflusal
0 Images
Cat. No.: HY-B0531
CAS No.: 322-79-2
Target:  

COX Phosphodiesterase (PDE) NF-κB NO Synthase Prostaglandin Receptor

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-κB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimer’s disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimer’s disease .
2-Iminobiotin
2-Iminobiotin
0 Images
Cat. No.: HY-118700
CAS No.: 13395-35-2
Purity:  99.88%
Synonyms: Guanidinobiotin
Target:  

NO Synthase

Research Areas:  

Neurological Disease

2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively . 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .
3-Amino-2-naphthoic acid
3-Amino-2-naphthoic acid
0 Images
Cat. No.: HY-W005148
CAS No.: 5959-52-4
3-Amino-2-naphthoic acid is a derivative of naphthalene and can be used to synthesize other compounds. 3-Amino-2-naphthoic acid is commonly used as the base material for synthesizing various dyes and pigments. 3-Amino-2-naphthoic acid has been developed as a "turn-on" fluorescence probe for the specific detection of the cyanate anion (CNO -) .
2-Iminobiotin hydrobromide
2-Iminobiotin hydrobromide
0 Images
Cat. No.: HY-118700A
CAS No.: 76985-52-9
Purity:  ≥98.0%
Synonyms: Guanidinobiotin hydrobromide
Target:  

NO Synthase

Research Areas:  

Neurological Disease

2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively . 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .
Triflusal-d3
Triflusal-d3
0 Images
Cat. No.: HY-B0531S
CAS No.: 2748541-63-9
Triflusal-d3 is deuterium labeled Triflusal (HY-B0531). Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-κB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimer’s disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimer’s disease .
Triflusal (Standard)
Triflusal (Standard)
0 Images
Cat. No.: HY-B0531R
CAS No.: 322-79-2
Target:  

Reference Standards COX Phosphodiesterase (PDE) NF-κB NO Synthase Prostaglandin Receptor

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Triflusal (Standard) is the analytical standard of Triflusal (HY-B0531). This product is intended for research and analytical applications. Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-κB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimer’s disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimer’s disease .
Assay Types