6 Results for "

CNS delivery

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "CNS delivery" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-A0168
CAS No.: 313348-27-5
Synonyms: CVT-3146
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease Cancer

Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
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Cat. No.: HY-P10502A
Target:  

LDLR

Research Areas:  

Others

L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 acetate exhibits high affinity to LRP1 with Ki of 45 nM. L57 acetate exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 acetate can be utilized as the carrier for CNS drug delivery .
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Cat. No.: HY-A0168A
CAS No.: 875148-45-1
Synonyms: CVT-3146 hydrate
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease

Regadenoson hydrate (NSC 169186) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson hydrate also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
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Cat. No.: HY-A0168R
CAS No.: 313348-27-5
Synonyms: CVT-3146 (Standard)
Regadenoson (Standard) is the analytical standard of Regadenoson. This product is intended for research and analytical applications. Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
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Cat. No.: HY-L0124V
13,082 compounds
The basic requirements for the compounds that are supposed to penetrate the blood-brain barrier are somewhat different from those for the majority of drug discovery projects. Alongside the known problem with delivery of the large and non-polar compounds and their penetrability through the cell membrane, the other issue arises as well: small and polar compounds are not able to pass the Blood-Brain Barrier. Chemspace CNS-focused library comprises quite small, non-polar compounds that are also free from PAINS/toxic fragments and aggregators.
Cat. No.: HY-180474
CAS No.: 3024403-65-1
Target:  

Liposome

Research Areas:  

Neurological Disease

LP293-p is a lipid with activated ester groups, which can be used for the synthesis of ATXN2 RNAi. LP293-p can be utilized to enhance the targeting of the central nervous system (CNS) .
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