1 Result for "

CP286

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CP286" in MCE Product Catalog:

Cat. No.: HY-181010
Target:  

HDAC Parasite

Research Areas:  

Infection

HDAC1-IN-12 is a Plasmodium falciparum HDAC1 (PfHDAC1) inhibitor with an IC50 of 4.1 nM against Pf3D7. HDAC1-IN-12 inhibits PfHDAC1, upregulates histone H3 acetylation in P. falciparum parasites, downregulates malaria invasion-related gene expression, and exhibits favorable safety profiles, improved physicochemical properties, and potent in vivo antimalarial activity. HDAC1-IN-12 can be used for the research of malaria .
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