1 Result for "

CST651

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CST651" in MCE Product Catalog:

Cat. No.: HY-134303
CAS No.: 2489241-16-7
Synonyms: PROTAC CDK4/6 degrader 34
Target:  

PROTACs CDK

Research Areas:  

Cancer

CST651 (PROTAC CDK4/6 degrader 34) is a selective cyclin-dependent kinase CDK4/6 PROTAC degrader with DC50 values of 20 nM and 5.1 nM, respectively. CST651 recruits the VHL E3 ubiquitin ligase to mediate the ubiquitination and proteasomal degradation of CDK4/6. CST651 inhibits cancer cell proliferation and migration. CST651 can be used in research related to breast cancer, multiple myeloma, acute myeloid leukemia, and acute lymphoblastic leukemia .
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