4 Results for "

CTR9

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CTR9" in MCE Product Catalog:

Cat. No.: HY-160267
CAS No.: 950403-60-8
Target:  

HIV DNA/RNA Synthesis

Research Areas:  

Infection Neurological Disease Cancer

iPAF1C is a inhibitor of the polymerase-associated factor 1 complex (PAF1C) with specific targeting to the PAF1 binding groove of CTR9 (a key subunit of PAF1C). iPAF1C disrupts PAF1C assembly by interfering with the PAF1-CTR9 interaction. iPAF1C selectively impairs BRD4-mediated recruitment of PAF1 to chromatin at hypoxia-responsive genes and inhibits RNA polymerase II (RNAPII) pause release. iPAF1C increases the population of HIV-1 NL4.3 Nef-IRES-GFP infected primary human CD4 +T cells in a dose-dependent manner. PAF1C can be used for the study of infection and diseases associated with abnormal hypoxic adaptation (e.g., cancers, neurological disorders) .
loading...
    loading...
Cat. No.: HY-RS03316
Research Areas:  

Others

CTR9 Human Pre-designed siRNA Set A contains three designed siRNAs for CTR9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS22131
Research Areas:  

Others

Ctr9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ctr9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS28653
Research Areas:  

Others

Ctr9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ctr9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
loading...
    loading...