1 Result for "

CTX439

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CTX439" in MCE Product Catalog:

Cat. No.: HY-182312
CAS No.: 2377487-13-1
Target:  

CDK Apoptosis

Research Areas:  

Cancer

CTX-439 is an orally active, ATP-competitive small-molecule inhibitor of CDK12 and CDK13, with an IC50 of 3.1 nM and a Kd of 0.38 nM against CDK12, and an IC50 of 9.2 nM against CDK13. CTX-439 induces DNA damage and apoptosis in tumor cells. CTX-439 is applicable for the research of breast cancer and ovarian cancer .
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