1 Result for "

CV-4-26

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CV-4-26" in MCE Product Catalog:

Cat. No.: HY-168085
Target:  

YAP Apoptosis

Research Areas:  

Cancer

CV-4-26 (Compound 22) is a covalent inhibitor of TEAD. CV-4-26 inhibits YAP/TEAD-based transcription, leading to the reduction of CTGF and CYR61 expression. CV-4-26 inhibits Huh7 and HepG2 cell colony formation, induces cell cycle arrest, and apoptosis. CV-4-26 shows antitumor activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB) .
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