1 Result for "

ClpP modulator-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "ClpP modulator-1" in MCE Product Catalog:

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Cat. No.: HY-175597
CAS No.: 2363753-48-2
Target:  

ClpP

Research Areas:  

Infection

ClpP modulator-1 (Compound BC8a), a peptidomimetic, is an allosteric ClpP modulator. ClpP modulator-1 is a ClpP activator at low concentration with EC50s of 0.35 and 0.58  μM for for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP), resepectively. ClpP modulator-1 also inhibits peptidase activity at high concentration by competitively inhibiting substrate protein (LY-AMC) binding to ClpP C sites. ClpP modulator-1 has antibacterial activity. ClpP modulator-1 can be used for bacterial infections research .
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