1 Result for "

Covidcil19

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Covidcil19" in MCE Product Catalog:

Cat. No.: HY-W728005
CAS No.: 1225177-95-6
Target:  

SARS-CoV

Research Areas:  

Infection

Covidcil-19 (compound C5) avidly binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with a Kd of 11 nM. Covidcil-19 stabilizes the hairpin’s folded state and impairs frameshifting in cells. Covidcil-19 reduces frameshifting efficiency of the SARS-CoV-2 FSE and does not affect SARS-CoV-2 FSE RNA levels. Covidcil-19 inhibits a process essential for SARS-CoV-2 viral propagation .
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