1 Result for "

Crizotinib-d8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Crizotinib-d8" in MCE Product Catalog:

Cat. No.: HY-50878S1
CAS No.: 1523579-82-9
Synonyms: PF-02341066-d8
Crizotinib-d8 (PF-02341066-d8) is deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition .
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