1 Result for "

CycleGPT

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CycleGPT" in MCE Product Catalog:

Cat. No.: HY-178936
CAS No.: 3094174-82-7
Target:  

JAK STAT

Research Areas:  

Inflammation/Immunology Cancer

JAK2-IN-15 is an orally active, potent, selective JAK2 inhibitor (IC50 = 1.17 nM). JAK2-IN-15 can inhibit the AK2-STAT signaling pathway. JAK2-IN-15 significantly improves key pathological indicators such as hematocrit and splenomegaly in an Epoetin beta (HY-114134) (rhEPO)-induced mouse model. JAK2-IN-15 can be used for the study of Polycythemia Vera (PV) .
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