1 Result for "

Cymserine

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Cymserine" in MCE Product Catalog:

Cat. No.: HY-182615
CAS No.: 145209-39-8
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Cymserine is a blood-brain barrier-permeable butyrylcholinesterase (BuChE) inhibitor with an IC50 value of 56.43 nM and a Ki of 38 nM. Cymserine binds to the catalytic domain of BuChE in a concentration-dependent manner to form a stable carbamylated enzyme complex, and exhibits BuChE selectivity over acetylcholinesterase due to its structural compatibility with the larger acyl-binding pocket of BuChE. Cymserine can be used in the research of Alzheimer's disease .
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