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Results for "

D-01

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162601
    D-01

    		Histone Methyltransferase HIF/HIF Prolyl-Hydroxylase Cancer
    D-01 is a dual-targeting inhibitor of HIF-1α and EZH2 (IC50: 4.86 μM and 0.99 μM respectively). D-01 inhibits the expression of H3K27me3 protein. D-01 inhibits the migration, clone and the invasion of A549 cells, and also inhibits tube formation of HUVECs. D-01 can be used for research of lung cancer .
    D-01
  • HY-178260
    LM-D01

    		Drug-Linker Conjugates for ADC Cancer
    LM-D01 is a Drug-Linker Conjugates for ADC. LM-D01 consists of the ADC Cytotoxin Exatecan-3-amine (HY-178265) and a linker MC-GGFG-NH-CH2-O-propionic acid (HY-178266). LM-D01 can be used for synthesis of ADCs .
    LM-D01
  • HY-178266
    MC-GGFG-NH-CH2-O-propionic acid

    		ADC Linker Cancer
    MC-GGFG-NH-CH2-O-propionic acid is a ADC linker that can be used in the synthesis of LM-D01 (HY-178260) .
    MC-GGFG-NH-CH2-O-propionic acid
  • HY-P992166
    AB-004

    		ADC Antibody Collagen Cancer
    AB-004 is a humanized monoclonal antibody and ADC targeting uPARAP. AB-004 can be conjugated with the topoisomerase-1 inhibitor P1021 via a protease-cleavable tetrapeptide linker to form the ADC ADCE-D01. AB-004 binds to tumor cells expressing uPARAP, triggering the endocytosis of the ADC. AB-004 is applicable for cancer research .
    AB-004

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