2 Results for "

D-4-77

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "D-4-77" in MCE Product Catalog:

Cat. No.: HY-156734
Target:  

SARS-CoV Virus Protease

Research Areas:  

Infection

D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 0.95 μM. D-4-77 has antiviral active with an EC50 value of 0.49 μM. D-4-77 suppresses SARS-CoV-2 Mpro -induced antagonism of the host NF-κB innate immune response .
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Cat. No.: HY-18628S
UMI-77-d4 is the deuterium labeled UMI-77. UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
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