1 Result for "

DBCO-NHS ester 3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DBCO-NHS ester 3" in MCE Product Catalog:

Cat. No.: HY-115545
CAS No.: 1393350-27-0
Purity:  95.55%
Target:  

ADC Linkers

Research Areas:  

Cancer

DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) . DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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