1 Result for "

DC-PRC2in-01

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DC-PRC2in-01" in MCE Product Catalog:

Cat. No.: HY-178694
CAS No.: 120430-77-5
Research Areas:  

Cancer

DC-PRC2in-01 is a potent EZH2-EED interaction inhibitor with an IC50 of 4.21 μM and a Kd of 4.56 μM. DC-PRC2in-01 disrupts the EZH2-EED interaction, leading to degradation of PRC2 core proteins and decrease of H3K27me3 levels, inhibition of PRC2-driven lymphoma cell proliferation, and cell cycle arrest. DC-PRC2in-01 can be used for the research of PRC2-related cancers, such as Diffuse Large B-cell Lymphoma (DLBCL) and follicular lymphoma (FL) .
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