1 Result for "

DDO2728

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DDO2728" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-155489
CAS No.: 3029515-97-4
Purity:  98.55%
Research Areas:  

Cancer

DDO-2728 (compound 19) is a selective AlkB homologue 5 (ALKBH5) inhibitor with an IC50 of 2.97 μM. DDO-2728 increases the abundance of N 6 methyladenosine (m 6A) modifications, inducing cell apoptosis and cycle arrest. DDO-2728 suppresses tumor growth in the MV4 11 xenograft model with favorable safety profile, shows the potential of targeting ALKBH5 in cancer research .
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