1 Result for "

DDO4033

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DDO4033" in MCE Product Catalog:

Cat. No.: HY-175247
Research Areas:  

Cancer

DDO-4033 is a SPOP inhibitor (IC50 = 16.9 μM, Kd = 15.1 μM). DDO-4033 impairs the malignant migration, invasion, and proliferation of clear cell renal cell carcinoma (ccRCC) cell lines. DDO-4033 disrupts SPOP recruitment to its substrate LATS1, inhibits its polyubiquitination and subsequent degradation, and upregulates LATS1 expression. DDO-4033 has promising antitumor activity and is promising for renal cell carcinoma research .
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