17 Results for "

DOPE-PEG1000

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "DOPE-PEG1000" in MCE Product Catalog:

Cat. No.: HY-W591448
DOPE-PEG1000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-Azidecan be used in drug delivery research .
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Cat. No.: HY-155932
CAS No.: 474922-90-2
Synonyms: DOPE-PEG1000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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Cat. No.: HY-W440990
Synonyms: DOPE-PEG1000-NH2
DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-187326
Synonyms: DOPE-PEG1000-CSRNLIDC
DOPE-PEG1000-pPB (DOPE-PEG1000-CSRNLIDC) is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and platelet-derived growth factor receptor β-binding peptide (pPB peptide (HY-P11549)) as the terminal targeting/functional ligand. DOPE-PEG1000-pPB enables targeted delivery to fibrotic tissues and tumor stroma.
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Cat. No.: HY-187236
Synonyms: DOPE-PEG1000-APWHLSSQYSRT
DOPE-PEG1000-CTP is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and CTP (cardiotropic targeting peptide) (HY-P4094) as the terminal targeting/functional ligand. DOPE-PEG1000-CTP can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers, conferring cardiac targeting capability.
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Cat. No.: HY-W440826
DOPE-PEG1000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-COOHcan be used in drug delivery research .
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Cat. No.: HY-203300A
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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Cat. No.: HY-187317
DOPE-PEG1000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DOPE-PEG1000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
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Cat. No.: HY-187318
Synonyms: DOPE-PEG1000-Cys-SRNLIDC
DOPE-PEG1000-LyP-1 (DOPE-PEG1000-Cys-SRNLIDC) is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, PEG, and LyP-1 peptide (CGNKRTRGC) (HY-P2526) as the terminal targeting/functional ligand. LyP-1 is a cyclic 9-amino acid peptide that specifically binds to p32/gC1qR protein, which is highly expressed on tumor-associated macrophages, lymphatic endothelial cells, and certain tumor cells. DOPE-PEG1000-LyP-1 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against p32/gC1qR protein on the surface of lymphatic vessels, tumor-associated macrophages, and tumor cells.
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Cat. No.: HY-184571
DOPE-PEG1000-WYRGRL is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and WYRGRL peptide (HY-P10739)as the terminal targeting/functional ligand. DOPE-PEG1000-WYRGRL can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against specific cell surface receptors in tumor and inflammatory microenvironments.
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Cat. No.: HY-184576
DOPE-PEG1000-iRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and iRGD peptide (HY-P0122) as the terminal targeting/functional ligand. DOPE-PEG1000-iRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against sequential binding to αv integrins on tumor vasculature → neuropilin-1 (NRP1) in tumor tissue.
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Cat. No.: HY-184578
DOPE-PEG1000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DOPE-PEG1000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-184552
DOPE-PEG1000-T7 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and T7 peptide (HAIYPRH) as the terminal targeting/functional ligand. DOPE-PEG1000-T7 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against transferrin receptor (TfR/CD71) on the surface of cancer cells and brain endothelial cells.
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Cat. No.: HY-187278
DOPE-PEG1000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DOPE-PEG1000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
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Cat. No.: HY-187312
DOPE-PEG1000-GE11 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and GE11 peptide (YHWYGYTPQNVI) (HY-P10128) as the terminal targeting/functional ligand. DSG-PEG2000-GE11 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against EGFR (HER1) on the surface of various epithelial tumor cells (lung cancer, breast cancer, colorectal cancer, head and neck cancer).
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Cat. No.: HY-203300D
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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Cat. No.: HY-W1053112B
Synonyms: DOPE-PEG10000-NH2
DOPE-PEG10000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG10000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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