1 Result for "

DOV273547

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DOV273547" in MCE Product Catalog:

Cat. No.: HY-W001692
CAS No.: 96604-21-6
Synonyms: DOV 273547
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Ocinaplon (DOV 273547) is an orally active positive allosteric modulator of GABAA receptor, with an EC50 ranging from 3.07 μM (α1β2γ2 subtype) to 10.03 μM (α1β2γ3 subtype). Ocinaplon enhances GABA-stimulated chloride currents across multiple GABAA receptor subtypes, with varying potency between different subtypes. Ocinaplon exerts anxiolytic and anticonvulsant effects, and causes motor impairment at high doses. Ocinaplon can be used for research on generalized anxiety disorder .
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