1 Result for "

DRI-C21045

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DRI-C21045" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-120323
CAS No.: 2101765-81-3
Purity:  98.11%
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 μM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 μM and 4.5 μM, respectively .
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