1 Result for "

DYRKi

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DYRKi" in MCE Product Catalog:

Cat. No.: HY-119607
CAS No.: 1640364-04-0
Target:  

DYRK

Research Areas:  

Cancer

DYRKi is an inhibitor of DYRK1 and DYRK1B with IC50 values of 3.7 µM and 90 nM, respectively, which is used as a potent antagonist of Hh/Gli signaling. DYRKi impairs SMO-dependent and SMO-independent oncogenic GLI activity in human medulloblastoma cells. DYRKi is promising for research of HH/GLI-associated cancers .
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