1 Result for "

DuNE cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DuNE cells" in MCE Product Catalog:

Cat. No.: HY-168437
Target:  

MicroRNA

Research Areas:  

Cancer

LIN28-IN-2 is a Lin28 inhibitor with activity against Lin28a, Lin28b, and their zinc knuckle domain. LIN28-IN-2 blocks Lin28-RNA substrate binding, perturbs zinc knuckle domain conformation. LIN28-IN-2 inhibits cancer cell proliferation, spheroid growth, and induces G2/M phase arrest. LIN28-IN-2 suppresses cancer stem cell phenotypes, Lin28-mediated stress granule formation, let-7 target genes, cancer stem cell biomarkers, and neuroendocrine biomarkers expression in cancer cells. LIN28-IN-2 can be used for the research of cancer .
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