1 Result for "

Dusigitumab

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Dusigitumab" in MCE Product Catalog:

Cat. No.: HY-P99867
CAS No.: 1204390-13-5
Synonyms: MEDI 573

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Dusigitumab is a fully human IgG2λ monoclonal antibody that targets IGF-1 and IGF-2 with picomolar binding affinity. Dusigitumab blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R as well as activation of IR-A, thereby inhibiting the activation of downstream signaling pathways. Dusigitumab is applicable to research related to advanced solid tumors and hormone receptor-positive metastatic breast cancer .
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