1 Result for "

EFAD mouse models

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "EFAD mouse models" in MCE Product Catalog:

Cat. No.: HY-186284
CAS No.: 2245952-60-5
Target:  

Estrogen Receptor/ERR

Research Areas:  

Neurological Disease Endocrinology

EGX358 is a selective, orally active estrogen receptor β (ERβ) agonist with an EC50 of 27.4 nM for ERβ. EGX358 enhances object recognition ability, spatial memory and memory consolidation, and attenuates drug-induced vasomotor responses. EGX358 alleviates partial uterine atrophy without inducing uterine hypertrophy, while it does not alter anxiety-like behavior, depression-like behavior or body weight. EGX358 can be used in research related to Alzheimer's disease and menopause .
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