1 Result for "

ETM305

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "ETM305" in MCE Product Catalog:

Cat. No.: HY-177966
CAS No.: 250159-76-3
ETM-305 is a degradation product of the anticancer agent ET-743 (HY-50936). ET-743 (Ecteinascidin 743; Trabectedin) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks the transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cell apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin is used in the research of soft tissue sarcoma and ovarian cancer .
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