1 Result for "

EVT302

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "EVT302" in MCE Product Catalog:

Cat. No.: HY-16731
CAS No.: 676479-06-4
Synonyms: EVT 302; RG1577; RO4602522
Sembragiline (EVT 302) is a potent, selective and reversible monoamine oxidase B (MAO-B) inhibitor. Sembragiline reduces the metabolism of dopamine and other amine neurotransmitters by inhibiting the activity of the MAO-B enzyme, thereby potentially increasing the concentration of these neurotransmitters in the brain. Inhibition of the MAO-B enzyme also reduces the formation of toxic reactive oxygen species (ROS) that play a role in the pathological process of AD. Sembragiline has good oral activity and blood-brain barrier permeability. Sembragiline can be used in studies of AD, especially in patients with AD who show increased MAO-B activity .
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