1 Result for "

EXP-3174 d4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "EXP-3174 d4" in MCE Product Catalog:

Cat. No.: HY-12765S
CAS No.: 1246820-62-1
Purity:  98.17%
Synonyms: E-3174 d4; EXP-3174 d4
Losartan-d4 carboxylic acid (E-3174-d4) is the deuterium labeled Losartan Carboxylic Acid (HY-12765). Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure.
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