1 Result for "

EYE002

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EYE002" in MCE Product Catalog:

Cat. No.: HY-175663
Target:  

RPE65

Research Areas:  

Metabolic Disease

EYE-002 is a RPE65 inhibitor with an IC50 of 69 nM. EYE-002 promotes recovery of scotopic ERG a-/b-wave amplitudes. EYE-002 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-002 exerts protective effects against photic retinal damage in mice. EYE-002 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
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