3 Results for "

Entacapone-d10

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Entacapone-d10" in MCE Product Catalog:

Cat. No.: HY-14280S
CAS No.: 1185241-19-3
Pureté:  ≥98.0%
Entacapone-d10 is the deuterium labeled Entacapone. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 μM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
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Cat. No.: HY-W704878
CAS No.: 1185241-19-3
(Z)-Entacapone-d10-1 is the deuterium labeled (Z)-Entacapone (HY-139089). (Z)-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone (HY-14280). It is also a potential impurity found in commercial preparations of Entacapone and a degradant of Entacapone formed by UV light exposure.
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Cat. No.: HY-139089S
(Z)-Entacapone-d10 is the deuterium labeled (Z)-Entacapone .
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