1 Result for "

F44-S101

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "F44-S101" in MCE Product Catalog:

Cat. No.: HY-181876
CAS No.: 3124701-00-1
Target:  

FXR

Research Areas:  

Metabolic Disease

F44-S101 is an orally active, potent, and selective gut-restricted FXR antagonist with an IC50 of 0.48 μM and lipid-lowering activity. F44-S101 selectively antagonizes intestinal FXR, feedback-activates hepatic FXR, promotes cholesterol metabolism and reduces lipid accumulation. F44-S101 decreases total cholesterol, triglyceride and low-density lipoprotein cholesterol levels. F44-S101 can be used in studies related to hyperlipidemia .
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