3 Results for "

FC-131

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "FC-131" in MCE Product Catalog:

Cat. No.: HY-P1104
CAS No.: 606968-52-9
Target:  

CXCR Akt Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

FC131 is a CXCR4 antagonist that inhibits AKT kinase activity in AML OCI-AML3 cells. D-ArgFC131, a derivative of FC131, inhibits the phosphorylation of downstream ERK1/2 and Akt, induces caspase-3 pathway-mediated apoptosis, and causes cell cycle arrest. FC131 exerts cytotoxic effects in cancer cells such as AML cells. FC131 is applicable for cancer-related research .
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Cat. No.: HY-P1104A
CAS No.: 842166-42-1
Target:  

CXCR Akt Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

FC131 TFA is a CXCR4 antagonist that inhibits AKT kinase activity in AML OCI-AML3 cells. D-ArgFC131, a derivative of FC131 TFA, inhibits the phosphorylation of downstream ERK1/2 and Akt, induces caspase-3 pathway-mediated apoptosis, and causes cell cycle arrest. FC131 TFA exerts cytotoxic effects in cancer cells such as AML cells. FC131 TFA is applicable for cancer-related research .
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Cat. No.: HY-W104862
CAS No.: 102281-45-8
Synonyms: 4-NH2-d-Phe
Target:  

CXCR

Research Areas:  

Inflammation/Immunology

4-Amino-D-phenylalanine ([D-Phe(4-NH2)), a cyclic pentapeptide, inhibits CXCL12 binding to CXCR4 in FC131, with an IC50 of 0.1 μM .
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