3 Results for "

FGFR1c

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "FGFR1c" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P990964
CAS No.: 2765640-39-7
Synonyms: BOS-580; LLF580

Target:  

FGFR

Efimosfermin alfa is a genetically engineered FGF21 variant. Efimosfermin alfa exerts its function by activating the FGFR1c/β-Klotho complex. Efimosfermin alfa is applicable to researches on metabolic dysfunction-associated steatohepatitis, obesity and mild hypertriglyceridemia [1] .
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Cat. No.: HY-P99614
CAS No.: 2517935-02-1
Synonyms: BFKB8488A; RG-7992; RO-7040551

Target:  

FGFR

Research Areas:  

Metabolic Disease

Fazpilodemab (BFKB8488A) is a humanized bispecific IgG1 antibody that selectively targets and activates fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD) [1].
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Cat. No.: HY-150687
CAS No.: 1010888-06-8
Target:  

ERK

Research Areas:  

Metabolic Disease

ZINC12409120 is a high selective ERK inhibitor. ZINC12409120 acts on disrupting FGF23:α-Klotho interaction to inhibit ERK activity with an IC50 of 5.0 μM [1].
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