1 Result for "

FQI2-34

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FQI2-34" in MCE Product Catalog:

Cat. No.: HY-180913
CAS No.: 2762499-38-5
Target:  

Connective Peptide

Research Areas:  

Cancer

FQI2-34 is an orally active TFCP2 (LSF) small molecule allosteric inhibitor. FQI2-34 directly binds to the LSF protein (Ki = 63 nM), inhibits the oligomerization of LSF, efficiently suppresses the transcriptional activity of LSF (IC₅₀ = 48 nM), and interferes with the SF-DNA interaction. FQI2-34 exhibits significant anti-proliferative activity against Huh7 cells and induces tumor regression in mouse models. FQI2-34 can be used for research on liver cancer .
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