2762499-38-5
Chemical Structure
FQI2-34
- CAS No.: 2762499-38-5
- Formula:C20H20N2O4
- Molecular Weight:352.38
InChIKey: AOAHNHDKGGUAMF-UHFFFAOYSA-N
SMILES: O=C1NC2=CC3=C(C=C2C(C4=CC=C(C=C4OCC)N(C)C)=C1)OCO3
Biological Activity: FQI2-34 is an orally active TFCP2 (LSF) small molecule allosteric inhibitor. FQI2-34 directly binds to the LSF protein (Ki = 63 nM), inhibits the oligomerization of LSF, efficiently suppresses the transcriptional activity of LSF (IC₅₀ = 48 nM), and interferes with the SF-DNA interaction. FQI2-34 exhibits significant anti-proliferative activity against Huh7 cells and induces tumor regression in mouse models. FQI2-34 can be used for research on liver cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FQI2-34 | 99.80% | FQI2-34 is an orally active TFCP2 (LSF) small molecule allosteric inhibitor. FQI2-34 directly binds to the LSF protein (Ki = 63 nM), inhibits the oligomerization of LSF, efficiently suppresses the transcriptional activity of LSF (IC₅₀ = 48 nM), and interferes with the SF-DNA interaction. FQI2-34 exhibits significant anti-proliferative activity against Huh7 cells and induces tumor regression in mouse models. FQI2-34 can be used for research on liver cancer. | ||||||||||||||||||||
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Keywords
