1 Result for "

FYJ195

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FYJ195" in MCE Product Catalog:

Cat. No.: HY-184161
Target:  

FLT3 STAT Akt ERK Apoptosis

Research Areas:  

Cancer

FYJ-195 is a potent orally active FLT3 inhibitor targeting FLT3 and its variants FLT3-ITD, FLT3-F691L, FLT3-D835V, FLT3-D835Y. FYJ-195 blocks FLT3 autophosphorylation and downstream STAT5, AKT, ERK signaling pathways, and induces apoptosis. FYJ-195 induces tumor regression in mouse acute myeloid leukemia (AML) xenograft models. FYJ-195 can be used for the research of AML .
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