1 Result for "

G 963

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "G 963" in MCE Product Catalog:

Cat. No.: HY-182538
CAS No.: 1009330-74-8
Target:  

MEK

Research Areas:  

Cancer

G-963 is an allosteric inhibitor of mitogen-activated protein kinase kinase (MEK) with a MEK1 IC50 of 0.012 μM. G-963 interacts with Ser212 of MEK and exhibits potent antiproliferative activity against HCT116 colon cancer cells (EC50 = 0.120 μM) and A375 melanoma cells (EC50 = 0.025 μM). G-963 can be used for the research of colon cancer, melanoma .
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