1 Result for "

G-6599

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "G-6599" in MCE Product Catalog:

Cat. No.: HY-173351
CAS No.: 2901806-51-5
Target:  

SWI/SNF Complex

Research Areas:  

Cancer

G-6599 is a monovalent molecular glue-like degrader of SMARCA2/SMARCA4. G-6599 covalently binds to a specific cysteine residue of the E3 ligase FBXO22 in a biotransformation-independent manner, promotes the formation of a ternary complex with SMARCA2/A4, and achieves efficient and specific degradation of the two proteins via the ubiquitin-proteasome pathway. G-6599 is applicable to the research of androgen-dependent prostate cancer and mutant non-small cell lung cancer .
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