2 Results for "

GDF15-GFRAL axis

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "GDF15-GFRAL axis" in MCE Product Catalog:

Cat. No.: HY-P990635

Target:  

TGF-β Receptor

Research Areas:  

Cancer

NGM-120 is a fully humanized IgG1 monoclonal antibody targeting GFRAL, which functions by blocking the GDF15-GFRAL axis. NGM-120 reduces serum GDF15 levels, increases body weight, expands central memory and proliferative CD8 + T cell populations, and decreases immunosuppressive and naive regulatory T cell populations. NGM-120 can be used for research on advanced prostate cancer .
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Cat. No.: HY-P992393

Target:  

TGF-β Receptor

Research Areas:  

Cancer

JMT203 is a monoclonal antibody against GFRAL and a body weight gain inducer. JMT203 induces early-onset, sustained and progressive body weight gain in cancer cachexia. JMT203 can be used for research related to cancer cachexia .
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