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NGM-120

Customer Review

Based on 1 Customer Validation

NGM-120 is a fully humanized IgG1 monoclonal antibody targeting GFRAL, which functions by blocking the GDF15-GFRAL axis. NGM-120 reduces serum GDF15 levels, increases body weight, expands central memory and proliferative CD8+ T cell populations, and decreases immunosuppressive and naive regulatory T cell populations. NGM-120 can be used for research on advanced prostate cancer.

For research use only. We do not sell to patients.

  • Purity : 99.50%
  • Molecular Weight:145.7 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for NGM-120
  • NGM-120 Chemical Structure
    NGM-120 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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NGM-120 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
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Top Publications Citing

Use of MCE Products

All TGF-beta/Smad Isoforms

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100 mg

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Assay Types
  • 1/16

    Immobilized GFRAL Protein, Human can bind NGM-120. The EC50 for this effect is 16.84 ng/mL.

  • NGM-120 Chemical Structure
    1/16
  • NGM-120
  • Immobilized GFRAL Protein, Human can bind NGM-120. The EC50 for this effect is 16.84 ng/mL.