1 Result for "

GMI1070

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GMI1070" in MCE Product Catalog:

Cat. No.: HY-125475
CAS No.: 927881-99-0
Synonyms: GMI-1070
Target:  

E-Selectin

Research Areas:  

Cardiovascular Disease

Rivipansel is a small-molecule glycomimetic pan-selectin antagonist with inhibitory activity against E-selectin and P-selectin. Rivipansel binds tightly to the lectin domain of E-selectin, and selectively blocks the recognition of CD62L by E-selectin without affecting the binding of PSGL-1 to E-selectin. Rivipansel functionally inhibits the adhesion of hematopoietic cells to endothelial cells, and is applicable to research related to sickle cell disease .
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