1 Result for "

GNF362

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GNF362" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-126750
CAS No.: 1003019-41-7
Purity:  99.86%
Target:  

Phosphatase

Research Areas:  

Inflammation/Immunology

GNF362 is a selective, potent, and orally bioavailable inhibitor of inositol trisphosphate 3’ kinase B (Itpkb) with an IC50 of 9 nM. GNF362 also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively. Inositol trisphosphate 3’ kinase B (Itpkb) is a Ca 2+-dependent kinase, which phosphorylates the 3’ position of Ins (1,4,5) P3 to generate inositol 1,3,4,5-tetrakisphosphate [Ins (1,3,4,5) P4] .
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