2 Results for "

GSDMB

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "GSDMB" in MCE Product Catalog:

Fidasimtamab
Fidasimtamab
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Cat. No.: HY-P99618
CAS No.: 2377419-89-9
Synonyms: IBI-315; BH2950

Target:  

EGFR PD-1/PD-L1

연구분야:  

Cancer

Fidasimtamab is a bispecific antibody targeting human epidermal growth factor receptor 2 (Her2) and programmed death protein 1 (PD-1), with a Ka of 3.55e-10 M for human Her2 and a Ka of 1.17e-9 M for human PD-1. Fidasimtamab cross-links Her2-positive tumor cells with PD-1-positive T cells to form immune synapses, blocks PD-1-ligand interactions, preserves antibody-dependent cellular cytotoxicity, induces gasdermin B (GSDMB)-mediated pyroptosis, and activates T cells. Fidasimtamab is applicable to relevant research on Her2-positive gastric cancer .
GSDMB Human Pre-designed siRNA Set A
GSDMB Human Pre-designed siRNA Set A
Cat. No.: HY-RS05855
Target:  

Small Interfering RNA (siRNA)

연구분야:  

Others

GSDMB Human Pre-designed siRNA Set A contains three designed siRNAs for GSDMB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Assay Types