1 Result for "

GSK 046

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "GSK 046" in MCE Product Catalog:

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4 Cited Publications
Cat. No.: HY-136571
CAS No.: 2474876-09-8
Purity:  99.65%
Synonyms: iBET-BD2
Research Areas:  

Inflammation/Immunology

GSK046 (iBET-BD2), a chemical probe, is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. GSK046 has immunomodulatory activity .
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