1 Result for "

GSK114

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "GSK114" in MCE Product Catalog:

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Cat. No.: HY-117658
CAS No.: 1301761-96-5
Pureté:  99.52%
Target:  

MAP3K

Domaines de recherche:  

Cardiovascular Disease

GSK-114 is a highly selective, orally active TNNI3K inhibitor (IC50= 25 nM). GSK-114 shows a 40-fold selectivity for TNNI3K over B-Raf kinase (IC50= 1 μM). Cardiac troponin I-interacting kinase (TNNI3K or CARK) is a member of the tyrosine-like kinase family that is selectively expressed in heart tissue .
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