1 Result for "

GSK823093

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "GSK823093" in MCE Product Catalog:

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Cat. No.: HY-167680
CAS No.: 483369-58-0
Synonyms: GSK823093
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .
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