2 Results for "

H77-77

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "H77-77" in MCE Product Catalog:

Cat. No.: HY-124331
CAS No.: 21618-99-5
Target:  

Monoamine Oxidase

Research Areas:  

Neurological Disease

H77-77 is a selective MAO-A inhibitor with blood-brain barrier permeability, exhibiting an IC50 of 7.4 μM against rat MAO-A. H77-77 accumulates via uptake by serotonergic and noradrenergic neurons. H77-77 releases norepinephrine and serotonin from intracellular neuronal storage sites. H77-77 can be used in studies related to neurological disorders .
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Cat. No.: HY-P2647
CAS No.: 82131-82-6
Research Areas:  

Cardiovascular Disease

H-77 is a selective Renin inhibitor with an IC50 of 1.2 μM. H-77 causes dose-dependent decreases in plasma angiotensin I, plasma angiotensin II, and mean arterial pressure in sodium-depleted conscious beagle dogs. H-77 does not alter blood pressure or plasma angiotensin II levels in conscious chronically cannulated rats. H-77 can be used in studies related to the physiological and pathological states of the renin-angiotensin system .
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