1 Result for "

HC-5404-Fu

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HC-5404-Fu" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-157231A
CAS No.: 3034479-99-4
Purity:  98.92%
Target:  

PERK

Research Areas:  

Cancer

HC-5404-Fu is an orally active PERK inhibitor with an IC50 of 0.001 μM against human PERK. HC-5404-Fu blocks PERK activation induced by VEGFR-TKI and disrupts the adaptive stress response triggered by VEGFR-TKI. HC-5404-Fu enhances anti-angiogenic effects by inhibiting newly formed and mature tumor blood vessels in renal cell carcinoma models. HC-5404-Fu can be used in research related to renal cell carcinoma .
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