4 Results for "

HCC1428

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HCC1428" in MCE Product Catalog:

19
19 Cited Publications
Cat. No.: HY-19822
CAS No.: 722533-56-4
Synonyms: RAD1901
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo .
loading...
    loading...
19
19 Cited Publications
Cat. No.: HY-19822A
CAS No.: 1349723-93-8
Synonyms: RAD1901 dihydrochloride
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo .
loading...
    loading...
Cat. No.: HY-139659
CAS No.: 2316837-08-6
Purity:  99.68%
ARD-61 is a highly potent, effective and specific PROTAC androgen receptor (AR) degrader. ARD-61 potently and effectively induces AR and progesterone receptors (PR) degradation in AR+ cancer cell lines. ARD-61 induces apoptosis and effectively induces tumor growth inhibition in the MDA-MB-453 xenograft model in mice . ARD-61 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...
Cat. No.: HY-19822S2
Synonyms: RAD1901-d10
Elacestrant-d10 is the deuterium labeled of Elacestrant (HY-19822). Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also inhibits growth of ER + breast cancer cell lines in vitro and in vivo .
loading...
    loading...