1 Result for "

HDSI18

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HDSI18" in MCE Product Catalog:

Cat. No.: HY-172873
Target:  

HDAC Caspase Apoptosis

Research Areas:  

Cancer

HDSI-18 is an orally active HDAC6 selective inhibitor (IC50: 1.6 nM). HDSI-18 is cytotoxic to K562, MV4-11, MOLM-13, THP-1, and Jurkat cells (IC50: 0.48, 0.58, 0.91, 1.79, and 4.31 μM, respectively). HDSI-18 activates Caspase-3, induces mitochondrial depolarization and apoptosis, and has antitumor activity .
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